Protein Domains (also known as Protein Domain, Domain, Protein): Discrete protein structural units that may fold independently of the rest of the protein and have their own functions.

NIH MeSH · D000072417Phenomena and Processes

Protein Domains

Also known asProtein Domain · Domain, Protein · Domains, Protein · Peptide Domain · Domain, Peptide · Domains, Peptide · Peptide Domains

Definition

Discrete protein structural units that may fold independently of the rest of the protein and have their own functions.

MeSH classification

  • G02.111.570.820.709.275.750
  • G02.111.570.820.709.610.500

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Related concepts

AAA Domain

An approximately 250 amino acid domain common to AAA ATPases and AAA Proteins. It consists of a highly conserved N-terminal P-Loop ATPase su…

Amino Acid Motifs

Three-dimensional protein structural elements that are composed of a combination of secondary structures. They include HELIX-LOOP-HELIX MOTI…

Ankyrin Repeat

Protein motif that contains a 33-amino acid long sequence that often occurs in tandem arrays. This repeating sequence of 33-amino acids was …

AT-Hook Motifs

DNA-binding motifs, first described in one of the HMGA PROTEINS: HMG-I(Y) PROTEIN. They consist of positively charged sequences of nine amin…

B30.2-SPRY Domain

A protein interaction domain that is characterized by a bent beta-sandwich consisting of two antiparallel beta-sheets. It occurs in eukaryot…

BTB-POZ Domain

A homodimerization protein interaction domain occurring at the N terminus of proteins that contain multiple copies of either CYS2-HIS2 ZINC …

C2 Domains

Protein modules that function in the targeting of proteins to CELL MEMBRANES. They consist of an eight-stranded anti-parallel beta-sandwich …

Carbohydrate Binding Modules

Contiguous amino acid sequences within a carbohydrate-active enzyme with discrete folds having carbohydrate binding activity. They are class…

Common questions about Protein Domains

What does Protein Domains mean in medicine?
Discrete protein structural units that may fold independently of the rest of the protein and have their own functions. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is Protein Domains known by any other names?
Yes. Protein Domains is also referred to as Protein Domain, Domain, Protein, Domains, Protein, Peptide Domain in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does Protein Domains sit in the medical classification?
Protein Domains falls under the broader medical category "Phenomena and Processes" in the MeSH hierarchy (tree numbers: G02.111.570.820.709.275.750, G02.111.570.820.709.610.500). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of Protein Domains?
For a plain-language explanation of Protein Domains - including symptoms, treatments and what it means for an Indian patient - ask GoDavaii's Health AI. It works in 22+ Indian languages, is free and needs no signup. Tap "Ask GoDavaii AI about Protein Domains" above.

Source: NIH MeSH 2026 (D000072417) — National Library of Medicine, public domain. View official MeSH record ↗