Ankyrin Repeat (also known as Repeat, Ankyrin, Repeats, Ankyrin): Protein motif that contains a 33-amino acid long sequence that often occurs in tandem arrays. This repeating sequence of 33-amino acids was discovered in ANKYRIN where it is involved in interaction with the anion exchanger (ANION EXCHANGE PROTEIN 1, ERYT

NIH MeSH · D017089Phenomena and Processes

Ankyrin Repeat

Also known asRepeat, Ankyrin · Repeats, Ankyrin · ANK Repeat · ANK Repeats · Repeat, ANK · Repeats, ANK · Ankyrin Repeats · Ankyrin-Like Repeats · Ankyrin-Like Repeat · Ankyrin Like Repeats · Repeat, Ankyrin-Like · Repeats, Ankyrin-Like

Definition

Protein motif that contains a 33-amino acid long sequence that often occurs in tandem arrays. This repeating sequence of 33-amino acids was discovered in ANKYRIN where it is involved in interaction with the anion exchanger (ANION EXCHANGE PROTEIN 1, ERYTHROCYTE). Ankyrin repeats cooperatively fold into domains that mediate molecular recognition via protein-protein interactions.

MeSH classification

  • G02.111.570.060.720.030
  • G02.111.570.820.709.275.500.030
  • G02.111.570.820.709.275.750.500.080
  • G02.111.570.820.709.275.875.030

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Common questions about Ankyrin Repeat

What does Ankyrin Repeat mean in medicine?
Protein motif that contains a 33-amino acid long sequence that often occurs in tandem arrays. This repeating sequence of 33-amino acids was discovered in ANKYRIN where it is involved in interaction with the anion exchanger (ANION EXCHANGE PROTEIN 1, ERYTHROCYTE). Ankyrin repeats cooperatively fold into domains that mediate molecular recognition via protein-protein interactions. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is Ankyrin Repeat known by any other names?
Yes. Ankyrin Repeat is also referred to as Repeat, Ankyrin, Repeats, Ankyrin, ANK Repeat, ANK Repeats in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does Ankyrin Repeat sit in the medical classification?
Ankyrin Repeat falls under the broader medical category "Phenomena and Processes" in the MeSH hierarchy (tree numbers: G02.111.570.060.720.030, G02.111.570.820.709.275.500.030, G02.111.570.820.709.275.750.500.080). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of Ankyrin Repeat?
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Source: NIH MeSH 2026 (D017089) — National Library of Medicine, public domain. View official MeSH record ↗