AAA Domain
Also known asAAA Modules · AAA Module · Module, AAA · Modules, AAA · AAA+ Modules · AAA+ Module · Module, AAA+ · Modules, AAA+ · AAA Domains · Domain, AAA · Domains, AAA · AAA+ Domain
Definition
An approximately 250 amino acid domain common to AAA ATPases and AAA Proteins. It consists of a highly conserved N-terminal P-Loop ATPase subdomain with an alpha-beta-alpha conformation, and a less-conserved C-terminal subdomain with an all alpha conformation. The N-terminal subdomain includes Walker A and Walker B motifs which function in ATP binding and hydrolysis.
MeSH classification
- G02.111.570.820.709.275.500.913
Need clinical context, treatments, or patient-language explanation?
Ask GoDavaii AI about AAA DomainRelated concepts
Amino Acid Motifs
Three-dimensional protein structural elements that are composed of a combination of secondary structures. They include HELIX-LOOP-HELIX MOTI…
Ankyrin Repeat
Protein motif that contains a 33-amino acid long sequence that often occurs in tandem arrays. This repeating sequence of 33-amino acids was …
AT-Hook Motifs
DNA-binding motifs, first described in one of the HMGA PROTEINS: HMG-I(Y) PROTEIN. They consist of positively charged sequences of nine amin…
Source: NIH MeSH 2026 (D000074182) — National Library of Medicine, public domain. View official MeSH record ↗