AT-Hook Motifs
Also known asAT-Hook Motif · AT Hook Motifs · Motif, AT-Hook · Motifs, AT-Hook · AT Hooks · AT Hook · Hook, AT · Hooks, AT · AT Hook Motif · Motif, AT Hook · Motifs, AT Hook
Definition
DNA-binding motifs, first described in one of the HMGA PROTEINS: HMG-I(Y) PROTEIN. They consist of positively charged sequences of nine amino acids centered on the invariant tripeptide glycine-arginine-proline. They act to fasten the protein to an AT RICH SEQUENCE in the DNA.
MeSH classification
- G02.111.570.820.709.275.500.050
Need clinical context, treatments, or patient-language explanation?
Ask GoDavaii AI about AT-Hook MotifsRelated concepts
AAA Domain
An approximately 250 amino acid domain common to AAA ATPases and AAA Proteins. It consists of a highly conserved N-terminal P-Loop ATPase su…
Amino Acid Motifs
Three-dimensional protein structural elements that are composed of a combination of secondary structures. They include HELIX-LOOP-HELIX MOTI…
Ankyrin Repeat
Protein motif that contains a 33-amino acid long sequence that often occurs in tandem arrays. This repeating sequence of 33-amino acids was …
Source: NIH MeSH 2026 (D024761) — National Library of Medicine, public domain. View official MeSH record ↗