BTB-POZ Domain
Also known asBTB POZ Domain · BTB-POZ Domains · BTB Domain · BTB Domains · POZ Domain · POZ Domains · BTB (POZ) Domain · Broad-Complex, Tramtrack and Bric a Brac Domain · Broad Complex, Tramtrack and Bric a Brac Domain · POxvirus and Zinc Finger Domain
Definition
A homodimerization protein interaction domain occurring at the N terminus of proteins that contain multiple copies of either CYS2-HIS2 ZINC FINGERS or KELCH REPEATS. It is characterized by a tightly intertwined dimer with an extensive hydrophobic interface. A surface-exposed groove lined with conserved amino acids is formed at the dimer interface, suggesting a peptide-binding site. Many BTB proteins are transcriptional regulators that are thought to regulate CHROMATIN structure.
MeSH classification
- G02.111.570.820.709.275.750.500.343
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Source: NIH MeSH 2026 (D000071757) — National Library of Medicine, public domain. View official MeSH record ↗