Moderate Risk Can take together (with caution)

Can I Take Folic Acid and Methotrexate Together? — Safety Guide

Folic Acid and Methotrexate can generally be taken together with precautions. Folic acid reduces Methotrexate side effects.

Medically Reviewed by GoDavaii Health Team|Updated April 2026

Quick Answer

Folic Acid and Methotrexate can generally be taken together with precautions. Folic acid reduces Methotrexate side effects.

How They Interact

Folic acid reduces Methotrexate side effects.

Safety Guidelines

Take on different days. NOT on Methotrexate day.

Important Medical Disclaimer: This drug interaction information is for educational purposes only. Always consult your doctor or pharmacist before combining medicines. Individual responses may vary based on health conditions, dosage, and other factors. GoDavaii's AI assistant can provide additional guidance in 16 Indian languages.

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