Can I take Abacavir with Methotrexate?

Methadone: An increased methadone dose may be required in a small number of patients. Riociguat: The riociguat dose may need to be reduced. 7.1 Methadone In a trial of 11 HIV-1-infected subjects receiving methadone-maintenance therapy with 600 mg of abacavir sulfate twice daily (twice the currently recommended dose), oral methadone clearance increased [see Clinical Pharmacology ] .

This is general interaction text from the label of a product that contains Abacavir. It does not mention Methotrexate, so it does not show how Abacavir and Methotrexate affect each other. The verdict above comes from the GoDavaii interaction dataset. Ask your pharmacist to check both medicines' labels before you combine them.

Questions to ask your pharmacist

• Does Abacavir change how Methotrexate works, or the other way round?
• Should I take Abacavir and Methotrexate at different times of day?
• Which side effects should I watch for while taking both?
• Is there a better option if this combination does not suit me?

• Always tell your doctor/pharmacist about ALL medicines you take - prescriptions, OTC, supplements, and herbal products.
• Keep a current medicine list with doses and timings - photo on your phone is enough.
• Read medicine labels for timing (with food / empty stomach) before combining.
• Even 'safe' combinations need monitoring - note any unusual symptoms in the first few days.
• Use GoDavaii AI to double-check before adding any new medicine, supplement, or desi ilaaj.