Clinical Trial, Phase I (also known as Clinical Trial, Phase 1): Work that is the report of a pre-planned, usually controlled, clinical study of the safety and efficacy of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques based on a small number of healthy persons and conducted over the period of a

NIH MeSH · D017426Publication Characteristics

Clinical Trial, Phase I

Also known asClinical Trial, Phase 1

Definition

Work that is the report of a pre-planned, usually controlled, clinical study of the safety and efficacy of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques based on a small number of healthy persons and conducted over the period of about a year in either the United States or a foreign country.

MeSH classification

  • V03.175.250.100

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Common questions about Clinical Trial, Phase I

What does Clinical Trial, Phase I mean in medicine?
Work that is the report of a pre-planned, usually controlled, clinical study of the safety and efficacy of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques based on a small number of healthy persons and conducted over the period of about a year in either the United States or a foreign country. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is Clinical Trial, Phase I known by any other names?
Yes. Clinical Trial, Phase I is also referred to as Clinical Trial, Phase 1 in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does Clinical Trial, Phase I sit in the medical classification?
Clinical Trial, Phase I falls under the broader medical category "Publication Characteristics" in the MeSH hierarchy (tree numbers: V03.175.250.100). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of Clinical Trial, Phase I?
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Source: NIH MeSH 2026 (D017426) — National Library of Medicine, public domain. View official MeSH record ↗