Adaptive Clinical Trial (also known as Platform Trial, Platform Clinical Trial): Clinical study in which a prospectively planned opportunity is included to modify trial designs and hypotheses based on analysis of data from subjects in the study.

NIH MeSH · D000076362Publication Characteristics

Adaptive Clinical Trial

Also known asPlatform Trial · Platform Clinical Trial

Definition

Clinical study in which a prospectively planned opportunity is included to modify trial designs and hypotheses based on analysis of data from subjects in the study.

MeSH classification

  • V03.175.250.050

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Common questions about Adaptive Clinical Trial

What does Adaptive Clinical Trial mean in medicine?
Clinical study in which a prospectively planned opportunity is included to modify trial designs and hypotheses based on analysis of data from subjects in the study. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is Adaptive Clinical Trial known by any other names?
Yes. Adaptive Clinical Trial is also referred to as Platform Trial, Platform Clinical Trial in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does Adaptive Clinical Trial sit in the medical classification?
Adaptive Clinical Trial falls under the broader medical category "Publication Characteristics" in the MeSH hierarchy (tree numbers: V03.175.250.050). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of Adaptive Clinical Trial?
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Source: NIH MeSH 2026 (D000076362) — National Library of Medicine, public domain. View official MeSH record ↗