Moderate Risk Can take together (with caution)
Can I Take PPIs and Vitamin B12 Together? — Safety Guide
PPIs and Vitamin B12 can generally be taken together with precautions. Long-term PPIs reduce B12 absorption.
Medically Reviewed by GoDavaii Health Team|Updated April 2026
Quick Answer
PPIs and Vitamin B12 can generally be taken together with precautions. Long-term PPIs reduce B12 absorption.
How They Interact
Long-term PPIs reduce B12 absorption.
Safety Guidelines
Check B12 levels annually if on long-term PPIs.
Important Medical Disclaimer: This drug interaction information is for educational purposes only. Always consult your doctor or pharmacist before combining medicines. Individual responses may vary based on health conditions, dosage, and other factors. GoDavaii's AI assistant can provide additional guidance in 16 Indian languages.
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