Is Progesterone Safe During Pregnancy?
Progesterone supplements are safe and often essential to prevent miscarriage in early pregnancy.
Last reviewed: April 2026
Safety Summary
Progesterone supplements are safe and often essential to prevent miscarriage in early pregnancy.
Category B — Likely Safe
Animal studies show no risk, but limited human data available.
Trimester-by-Trimester Guide
1st Trimester (Weeks 1–12)
Often prescribed to prevent miscarriage. Safe and essential if prescribed.
2nd Trimester (Weeks 13–26)
Usually tapered off by week 12-14 unless high-risk.
3rd Trimester (Weeks 27–40)
Rarely needed. Doctor will advise.
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Frequently Asked Questions
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Ask GoDavaii AIMedical Disclaimer: Pregnancy safety information is based on available clinical data and FDA classifications. This page is for educational purposes only and does not substitute professional medical advice. Every pregnancy is different — consult your doctor or gynaecologist before taking any medicine. Drug safety classifications may have been updated; always verify current guidelines.