Important Safety Warning

Ibuprofen is classified as Avoid during pregnancy. Do not take this medicine without direct guidance from your obstetrician.

AvoidFDA D

Is Ibuprofen Safe During Pregnancy?

Ibuprofen should be AVOIDED during pregnancy, especially in the third trimester. It can affect baby's heart and kidneys.

Last reviewed: April 2026

Safety Summary

Ibuprofen should be AVOIDED during pregnancy, especially in the third trimester. It can affect baby's heart and kidneys.

Category D — Avoid If Possible

Evidence of human fetal risk. Only use if no safer alternative exists.

Trimester-by-Trimester Guide

1st Trimester (Weeks 1–12)

Avoid. May increase miscarriage risk.

2nd Trimester (Weeks 13–26)

Avoid. Can affect fetal kidney function.

3rd Trimester (Weeks 27–40)

NEVER use. Can cause premature closure of ductus arteriosus in baby's heart.

Brands Available in India

BrufenIbugesicCombiflam

Safer Alternatives During Pregnancy

Your doctor may suggest one of these alternatives. Always confirm with your obstetrician.

Paracetamol (safest pain reliever) Hot/cold compress Rest

Frequently Asked Questions

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Medical Disclaimer: Pregnancy safety information is based on available clinical data and FDA classifications. This page is for educational purposes only and does not substitute professional medical advice. Every pregnancy is different — consult your doctor or gynaecologist before taking any medicine. Drug safety classifications may have been updated; always verify current guidelines.