Use With CautionFDA C

Is Fluoxetine Safe During Pregnancy?

Fluoxetine can be used during pregnancy but Sertraline is generally preferred. Never stop antidepressants suddenly.

Last reviewed: April 2026

Safety Summary

Fluoxetine can be used during pregnancy but Sertraline is generally preferred. Never stop antidepressants suddenly.

Category C — Use Cautiously

Animal studies show adverse effects; weigh benefits vs. risks.

Trimester-by-Trimester Guide

1st Trimester (Weeks 1–12)

Discuss with doctor. Some data on first trimester risk. Sertraline preferred.

2nd Trimester (Weeks 13–26)

Monitor closely. Benefits usually outweigh risks.

3rd Trimester (Weeks 27–40)

Risk of neonatal effects. Doctor will plan tapering if needed.

Brands Available in India

FludacFlunilProdep

Safer Alternatives During Pregnancy

Your doctor may suggest one of these alternatives. Always confirm with your obstetrician.

Sertraline (preferred SSRI) Therapy Counseling

Frequently Asked Questions

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Medical Disclaimer: Pregnancy safety information is based on available clinical data and FDA classifications. This page is for educational purposes only and does not substitute professional medical advice. Every pregnancy is different — consult your doctor or gynaecologist before taking any medicine. Drug safety classifications may have been updated; always verify current guidelines.