Best Medicines for Itching (Pruritus) in India
Treat the cause. Regular unperfumed moisturisers help itchy, dry skin. Antihistamines help mainly when itching is caused by hives or allergy.
Last updated: October 2026
Cetirizine
Use: Antihistamine for itch relief. Works best when itching is caused by hives or allergy. Less proven for other causes of itch.
Side effects: Drowsiness
Side effects: Drowsiness. Antihistamine for itch relief. Works best when itching is caused by hives or allergy. Less proven for other causes of itch.
Calamine Lotion
Use: Soothing topical relief.
Side effects: Can dry the skin. Avoid using it on dry skin and use it only for a few days at a time.
Side effects: Can dry the skin. Avoid using it on dry skin and use it only for a few days at a time. Soothing topical relief.
Hydroxyzine
Use: For severe itching, especially at night.
Side effects: Drowsiness, so do not drive if affected. Can cause a dangerous heart rhythm problem (QT prolongation), especially with heart disease, low potassium or magnesium, or other medicines that affect heart rhythm. Older people should usually avoid it.
Side effects: Drowsiness, so do not drive if affected. Can cause a dangerous heart rhythm problem (QT prolongation), especially with heart disease, low potassium or magnesium, or other medicines that affect heart rhythm. Older people should usually avoid it. For severe itching, especially at night.
When to See a Doctor
If itching is severe, is all over your body or happens without a rash, keeps coming back or does not improve with self care, happens during pregnancy, or comes with yellow skin or eyes (jaundice).
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The medicines, Indian brands and advice on this page were checked against these treatment guides and product listings.
Medical Disclaimer: This information is for educational purposes only and does not replace professional medical advice. The medicines listed may require a prescription. Dosage, suitability, and safety depend on individual health conditions. Always consult a licensed doctor or pharmacist before starting any medication.