Randomized Controlled Trial: A work that reports on a clinical trial that involves at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a ran

NIH MeSH · D016449Publication Characteristics

Randomized Controlled Trial

Definition

A work that reports on a clinical trial that involves at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.

MeSH classification

  • V03.175.250.500.500

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Related concepts

Controlled Clinical Trial

A work that reports on a clinical trial involving one or more test treatments, at least one control treatment, specified outcome measures fo…

Equivalence Trial

Trial that aims to show a new treatment is no better and no worse than the standard treatment.

Common questions about Randomized Controlled Trial

What does Randomized Controlled Trial mean in medicine?
A work that reports on a clinical trial that involves at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is Randomized Controlled Trial known by any other names?
Randomized Controlled Trial is the canonical name in the MeSH vocabulary. There are no commonly used alternate names for this concept in the official NIH database.
Where does Randomized Controlled Trial sit in the medical classification?
Randomized Controlled Trial falls under the broader medical category "Publication Characteristics" in the MeSH hierarchy (tree numbers: V03.175.250.500.500). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of Randomized Controlled Trial?
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Source: NIH MeSH 2026 (D016449) — National Library of Medicine, public domain. View official MeSH record ↗