11-beta-Hydroxysteroid Dehydrogenases (also known as 11 beta Hydroxysteroid Dehydrogenases, Dehydrogenases, 11-beta-Hydroxysteroid): Hydroxysteroid dehydrogenases that catalyzes the reversible conversion of CORTISOL to the inactive metabolite CORTISONE. Enzymes in this class can utilize either NAD or NADP as cofactors.

NIH MeSH · D042842Chemicals and Drugs

11-beta-Hydroxysteroid Dehydrogenases

Also known as11 beta Hydroxysteroid Dehydrogenases · Dehydrogenases, 11-beta-Hydroxysteroid · Cortisone 11-Oxoreductase · 11-Oxoreductase, Cortisone · Cortisone 11 Oxoreductase · 11beta-Hydroxysteroid Dehydrogenase · 11beta Hydroxysteroid Dehydrogenase · Dehydrogenase, 11beta-Hydroxysteroid · 11-Hydroxysteroid Dehydrogenase · 11 Hydroxysteroid Dehydrogenase · Dehydrogenase, 11-Hydroxysteroid · 11B-Hydroxysteroid Dehydrogenase

Definition

Hydroxysteroid dehydrogenases that catalyzes the reversible conversion of CORTISOL to the inactive metabolite CORTISONE. Enzymes in this class can utilize either NAD or NADP as cofactors.

MeSH classification

  • D08.811.682.047.436.174
  • D08.811.682.047.820.100

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Related concepts

11-beta-Hydroxysteroid Dehydrogenase Type 1

A low-affinity 11 beta-hydroxysteroid dehydrogenase found in a variety of tissues, most notably in LIVER; LUNG; ADIPOSE TISSUE; vascular tis…

11-beta-Hydroxysteroid Dehydrogenase Type 2

An high-affinity, NAD-dependent 11-beta-hydroxysteroid dehydrogenase that acts unidirectionally to catalyze the dehydrogenation of CORTISOL …

17-Hydroxysteroid Dehydrogenases

A class of enzymes that catalyzes the oxidation of 17-hydroxysteroids to 17-ketosteroids. EC 1.1.-.

3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)

A 3-hydroxysteroid dehydrogenase which catalyzes the reversible reduction of the active androgen, DIHYDROTESTOSTERONE to 5 ALPHA-ANDROSTANE-…

3-Hydroxysteroid Dehydrogenases

Catalyze the oxidation of 3-hydroxysteroids to 3-ketosteroids.

Common questions about 11-beta-Hydroxysteroid Dehydrogenases

What does 11-beta-Hydroxysteroid Dehydrogenases mean in medicine?
Hydroxysteroid dehydrogenases that catalyzes the reversible conversion of CORTISOL to the inactive metabolite CORTISONE. Enzymes in this class can utilize either NAD or NADP as cofactors. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is 11-beta-Hydroxysteroid Dehydrogenases known by any other names?
Yes. 11-beta-Hydroxysteroid Dehydrogenases is also referred to as 11 beta Hydroxysteroid Dehydrogenases, Dehydrogenases, 11-beta-Hydroxysteroid, Cortisone 11-Oxoreductase, 11-Oxoreductase, Cortisone in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does 11-beta-Hydroxysteroid Dehydrogenases sit in the medical classification?
11-beta-Hydroxysteroid Dehydrogenases falls under the broader medical category "Chemicals and Drugs" in the MeSH hierarchy (tree numbers: D08.811.682.047.436.174, D08.811.682.047.820.100). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of 11-beta-Hydroxysteroid Dehydrogenases?
For a plain-language explanation of 11-beta-Hydroxysteroid Dehydrogenases - including symptoms, treatments and what it means for an Indian patient - ask GoDavaii's Health AI. It works in 22+ Indian languages, is free and needs no signup. Tap "Ask GoDavaii AI about 11-beta-Hydroxysteroid Dehydrogenases" above.

Source: NIH MeSH 2026 (D042842) — National Library of Medicine, public domain. View official MeSH record ↗