3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) (also known as 3 alpha-Hydroxysteroid Dehydrogenase, 3 alpha Hydroxysteroid Dehydrogenase): A 3-hydroxysteroid dehydrogenase which catalyzes the reversible reduction of the active androgen, DIHYDROTESTOSTERONE to 5 ALPHA-ANDROSTANE-3 ALPHA,17 BETA-DIOL. It also has acti

NIH MeSH · D045002Chemicals and Drugs

3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)

Also known as3 alpha-Hydroxysteroid Dehydrogenase · 3 alpha Hydroxysteroid Dehydrogenase · Dehydrogenase, 3 alpha-Hydroxysteroid · 3 alpha-Hydroxysteroid Dehydrogenase (B-Specific) · 3 alpha-Hydroxysteroid Oxidoreductase · 3 alpha Hydroxysteroid Oxidoreductase · Oxidoreductase, 3 alpha-Hydroxysteroid · 3alpha-Hydroxysteroid Dehydrogenase (B-specific) · 5 alpha-Dihydroprogesterone 3 alpha-Hydroxysteroid Oxidoreductase · 5 alpha Dihydroprogesterone 3 alpha Hydroxysteroid Oxidoreductase · 5-DP-3 alpha-HSO · NADPH-5 alpha-Dihydroprogesterone 3 alpha-Hydroxysteroid Oxidoreductase

Definition

A 3-hydroxysteroid dehydrogenase which catalyzes the reversible reduction of the active androgen, DIHYDROTESTOSTERONE to 5 ALPHA-ANDROSTANE-3 ALPHA,17 BETA-DIOL. It also has activity towards other 3-alpha-hydroxysteroids and on 9-, 11- and 15- hydroxyprostaglandins. The enzyme is B-specific in reference to the orientation of reduced NAD or NADPH.

MeSH classification

  • D08.811.682.047.436.350.100
  • D08.811.682.047.820.186

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Related concepts

Common questions about 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)

What does 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) mean in medicine?
A 3-hydroxysteroid dehydrogenase which catalyzes the reversible reduction of the active androgen, DIHYDROTESTOSTERONE to 5 ALPHA-ANDROSTANE-3 ALPHA,17 BETA-DIOL. It also has activity towards other 3-alpha-hydroxysteroids and on 9-, 11- and 15- hydroxyprostaglandins. The enzyme is B-specific in reference to the orientation of reduced NAD or NADPH. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) known by any other names?
Yes. 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) is also referred to as 3 alpha-Hydroxysteroid Dehydrogenase, 3 alpha Hydroxysteroid Dehydrogenase, Dehydrogenase, 3 alpha-Hydroxysteroid, 3 alpha-Hydroxysteroid Dehydrogenase (B-Specific) in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) sit in the medical classification?
3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) falls under the broader medical category "Chemicals and Drugs" in the MeSH hierarchy (tree numbers: D08.811.682.047.436.350.100, D08.811.682.047.820.186). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)?
For a plain-language explanation of 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) - including symptoms, treatments and what it means for an Indian patient - ask GoDavaii's Health AI. It works in 22+ Indian languages, is free and needs no signup. Tap "Ask GoDavaii AI about 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)" above.

Source: NIH MeSH 2026 (D045002) — National Library of Medicine, public domain. View official MeSH record ↗