High Risk Avoid combining
Can I Take St John's Wort and SSRIs Together? — Safety Guide
St John's Wort and SSRIs should be avoided together. Both increase serotonin. Serotonin syndrome risk.
Medically Reviewed by GoDavaii Health Team|Updated April 2026
Quick Answer
St John's Wort and SSRIs should be avoided together. Both increase serotonin. Serotonin syndrome risk.
How They Interact
Both increase serotonin. Serotonin syndrome risk.
Safety Guidelines
NEVER combine. St John's Wort interacts with many medicines.
Important Medical Disclaimer: This drug interaction information is for educational purposes only. Always consult your doctor or pharmacist before combining medicines. Individual responses may vary based on health conditions, dosage, and other factors. GoDavaii's AI assistant can provide additional guidance in 16 Indian languages.
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