Moderate Risk Can take together (with caution)

Can I Take Sertraline and NSAIDs Together? — Safety Guide

Sertraline and NSAIDs can generally be taken together with precautions. SSRIs + NSAIDs increase GI bleeding risk 3-4x.

Medically Reviewed by GoDavaii Health Team|Updated April 2026

Quick Answer

Sertraline and NSAIDs can generally be taken together with precautions. SSRIs + NSAIDs increase GI bleeding risk 3-4x.

How They Interact

SSRIs + NSAIDs increase GI bleeding risk 3-4x.

Safety Guidelines

Use Paracetamol preferably. If NSAID needed, add PPI for stomach protection.

Important Medical Disclaimer: This drug interaction information is for educational purposes only. Always consult your doctor or pharmacist before combining medicines. Individual responses may vary based on health conditions, dosage, and other factors. GoDavaii's AI assistant can provide additional guidance in 16 Indian languages.

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