Metoclopramide and Tramadol: High risk - avoid combining interaction. Avoid combining these medicines. High risk. Avoid taking Metoclopramide with Tramadol unless your pharmacist or doctor approves.

Drug InteractionHigh Risk - AvoidAI-VerifiedCategory · general

Can I take Metoclopramide with Tramadol?

Metoclopramide and Tramadol should not be combined without explicit medical guidance.

Brand names: Metoclopramide - Reglan (US); Tramadol - Ultram (US), Zydol (UK)

MetoclopramideMEDICINE ATramadolMEDICINE B
Avoid combining
Do not combine

Quick verdict

No - avoid combining Metoclopramide with Tramadol.

High Risk - Avoid. Do not combine.

Ask GoDavaii AI about this combination

Is it safe to take Metoclopramide with Tramadol? Explain the interaction, what to watch for, and safer timing.

Interaction text from an FDA label for a product containing Metoclopramide (not specific to Tramadol)

General label text, not a pair-specific study

Drug Interactions The effects of metoclopramide on gastrointestinal motility are antagonized by anticholinergic drugs and narcotic analgesics. Additive sedative effects can occur when metoclopramide is given with alcohol, sedatives, hypnotics, narcotics, or tranquilizers.

This is general interaction text from the label of a product that contains Metoclopramide. It does not mention Tramadol, so it does not show how Metoclopramide and Tramadol affect each other. The verdict above comes from the GoDavaii interaction dataset. Ask your pharmacist to check both medicines' labels before you combine them.

Questions to ask your pharmacist

  • Does Metoclopramide change how Tramadol works, or the other way round?
  • Should I take Metoclopramide and Tramadol at different times of day?
  • Which side effects should I watch for while taking both?
  • Is there a better option if this combination does not suit me?

Why to Avoid

Simple rules that protect you

  • Always tell your doctor/pharmacist about ALL medicines you take - prescriptions, OTC, supplements, and herbal products.
  • Keep a current medicine list with doses and timings - photo on your phone is enough.
  • Read medicine labels for timing (with food / empty stomach) before combining.
  • Do NOT combine Metoclopramide with Tramadol without explicit doctor approval.
  • Use GoDavaii AI to double-check before adding any new medicine, supplement, or desi ilaaj.

If you've already taken both medicines and feel unwell (unusual bleeding, severe stomach pain, confusion, breathing issues), get medical help now.

Emergency · 112
AI-Verified · Cross-checked against 93,000+ interaction database

Not medical advice

Individual responses vary based on dose, timing, health conditions, and other medicines. Always consult your doctor or pharmacist before combining medicines. For emergencies, call 112.

Source

FDA drug label for Metoclopramide (via openFDA). View source ↗

General label text for Metoclopramide; not a pair-specific study.

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