Can I take Acetylsalicylic Acid with Tramadol?

Table 2 includes clinically significant drug interactions with tramadol hydrochloride extended-release tablets. Table 2: Clinically Significant Drug Interactions with Tramadol Hydrochloride Extended-Release Tablets Inhibitors of CYP2D6 Clinical Impact: The concomitant use of tramadol hydrochloride extended-release tablets and CYP2D6 inhibitors may result in an increase in the plasma concentration ...

This is general interaction text from the label of a product that contains Tramadol. It does not mention Acetylsalicylic Acid, so it does not show how Acetylsalicylic Acid and Tramadol affect each other. The verdict above comes from the GoDavaii interaction dataset. Ask your pharmacist to check both medicines' labels before you combine them.

Questions to ask your pharmacist

• Does Acetylsalicylic Acid change how Tramadol works, or the other way round?
• Should I take Acetylsalicylic Acid and Tramadol at different times of day?
• Which side effects should I watch for while taking both?
• Is there a better option if this combination does not suit me?

• Always tell your doctor/pharmacist about ALL medicines you take - prescriptions, OTC, supplements, and herbal products.
• Keep a current medicine list with doses and timings - photo on your phone is enough.
• Read medicine labels for timing (with food / empty stomach) before combining.
• Even 'safe' combinations need monitoring - note any unusual symptoms in the first few days.
• Use GoDavaii AI to double-check before adding any new medicine, supplement, or desi ilaaj.