Can I take Digoxin with Tramadol Hydrochloride?
Digoxin and Tramadol Hydrochloride should not be combined without explicit medical guidance.
Brand names: Digoxin - Lanoxin (US); Tramadol Hydrochloride - Ultram (US)
Quick verdict
No - avoid combining Digoxin with Tramadol Hydrochloride.
High Risk - Avoid. Do not combine.
Is it safe to take Digoxin with Tramadol Hydrochloride? Explain the interaction, what to watch for, and safer timing.
Interaction text from an FDA label for a product containing Digoxin (not specific to Tramadol Hydrochloride)
General label text, not a pair-specific study
Digoxin has a narrow therapeutic index, increased monitoring of serum digoxin concentrations and for potential signs and symptoms of clinical toxicity is necessary when initiating, adjusting, or discontinuing drugs that may interact with digoxin. Prescribers should consult the prescribing information of any drug which is co-prescribed with digoxin for potential drug interaction information.
This is general interaction text from the label of a product that contains Digoxin. It does not mention Tramadol Hydrochloride, so it does not show how Digoxin and Tramadol Hydrochloride affect each other. The verdict above comes from the GoDavaii interaction dataset. Ask your pharmacist to check both medicines' labels before you combine them.
Questions to ask your pharmacist
- Does Digoxin change how Tramadol Hydrochloride works, or the other way round?
- Should I take Digoxin and Tramadol Hydrochloride at different times of day?
- Which side effects should I watch for while taking both?
- Is there a better option if this combination does not suit me?
Why to Avoid
Simple rules that protect you
- Always tell your doctor/pharmacist about ALL medicines you take - prescriptions, OTC, supplements, and herbal products.
- Keep a current medicine list with doses and timings - photo on your phone is enough.
- Read medicine labels for timing (with food / empty stomach) before combining.
- Do NOT combine Digoxin with Tramadol Hydrochloride without explicit doctor approval.
- Use GoDavaii AI to double-check before adding any new medicine, supplement, or desi ilaaj.
If you've already taken both medicines and feel unwell (unusual bleeding, severe stomach pain, confusion, breathing issues), get medical help now.
Emergency · 112Not medical advice
Individual responses vary based on dose, timing, health conditions, and other medicines. Always consult your doctor or pharmacist before combining medicines. For emergencies, call 112.
Source
FDA drug label for Digoxin (via openFDA). View source ↗
General label text for Digoxin; not a pair-specific study.
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