Can I take Dextromethorphan with Terbinafine?
Dextromethorphan and Terbinafine should not be combined without explicit medical guidance. FDA label for Terbinafine references interaction with Dextromethorphan. In studies in healthy subjects characterized as extensive metabolizers of dextromethorphan (antitussive drug and CYP2D6 probe substrate), terbinafine increases the dextromethorphan /dextrorphan metabolite ratio in urine by 16- to 97-fold on average.
Brand names: Dextromethorphan - Delsym (US); Terbinafine - Lamisil (Australia)
Quick verdict
No - avoid combining Dextromethorphan with Terbinafine.
Dextromethorphan and Terbinafine should not be combined without explicit medical guidance. FDA label for Terbinafine references interaction with Dextromethorphan. In studies in healthy subjects characterized as extensive metabolizers of dextromethorphan (antitussive drug and CYP2D6 probe substrate), terbinafine increases the dextromethorphan /dextrorphan metabolite ratio in urine by 16- to 97-fold on average.
Is it safe to take Dextromethorphan with Terbinafine? Explain the interaction, what to watch for, and safer timing.
How They Interact
The science in one sentence
FDA label for Terbinafine references interaction with Dextromethorphan. In studies in healthy subjects characterized as extensive metabolizers of dextromethorphan (antitussive drug and CYP2D6 probe substrate), terbinafine increases the dextromethorphan /dextrorphan metabolite ratio in urine by 16- to 97-fold on average.
Why this matters
FDA label for Terbinafine references interaction with Dextromethorphan. In studies in healthy subjects characterized as extensive metabolizers of dextromethorphan (antitussive drug and CYP2D6 probe substrate), terbinafine increases the dextromethorphan /dextrorphan metabolite ratio in urine by 16- to 97-fold on average.
Why to Avoid
Simple rules that protect you
- Always tell your doctor/pharmacist about ALL medicines you take - prescriptions, OTC, supplements, and herbal products.
- Keep a current medicine list with doses and timings - photo on your phone is enough.
- Read medicine labels for timing (with food / empty stomach) before combining.
- Do NOT combine Dextromethorphan with Terbinafine without explicit doctor approval.
- Use GoDavaii AI to double-check before adding any new medicine, supplement, or desi ilaaj.
If you've already taken both medicines and feel unwell (unusual bleeding, severe stomach pain, confusion, breathing issues), get medical help now.
Emergency · 112Not medical advice
Individual responses vary based on dose, timing, health conditions, and other medicines. Always consult your doctor or pharmacist before combining medicines. For emergencies, call 112.
Source
FDA drug label for Terbinafine (via openFDA). View source ↗
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