D57.45 (Sickle-cell thalassemia beta plus with crisis) is an umbrella ICD-10-CM medical diagnosis code in the Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism chapter. It identifies cases of sickle-cell thalassemia beta plus with crisis for clinical documentation, bill

ICD-10-CM · Category

D57.45 — Sickle-cell thalassemia beta plus with crisis

Chapter D50-D89: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

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Sub-codes under D57.45

D57.451Sickle-cell thalassemia beta plus with acute chest syndromeD57.452Sickle-cell thalassemia beta plus with splenic sequestrationD57.453Sickle-cell thalassemia beta plus with cereb vascular invlD57.454Sickle-cell thalassemia beta plus with dactylitisD57.458Sickle-cell thalassemia beta plus with crisis with oth compD57.459Sickle-cell thalassemia beta plus with crisis, unspecified

Related diagnoses

D57.40Sickle-cell thalassemia without crisisD57.41Sickle-cell thalassemia, unspecified, with crisisD57.42Sickle-cell thalassemia beta zero without crisisD57.43Sickle-cell thalassemia beta zero with crisisD57.44Sickle-cell thalassemia beta plus without crisis

Common questions about D57.45 (Sickle-cell thalassemia beta plus with crisis)

What does ICD-10 code D57.45 mean?
D57.45 is the ICD-10-CM 2025 code for Sickle-cell thalassemia beta plus with crisis. ICD-10-CM is the medical coding system used by clinicians, hospitals and insurers worldwide to classify diseases and conditions in a standard way.
Is D57.45 a billable diagnosis code?
D57.45 is a category-level (umbrella) code rather than a billable specific code. For billing purposes, clinicians typically use a more specific sub-code under D57.45. Browse the sub-codes listed on this page.
Which ICD-10 chapter does D57.45 belong to?
D57.45 belongs to the chapter "Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism" (codes D50-D89). ICD-10-CM organises codes into 22 chapters by body system or condition type, which helps clinicians navigate related diagnoses.
Where can I get plain-language information about Sickle-cell thalassemia beta plus with crisis?
For a plain-language explanation of Sickle-cell thalassemia beta plus with crisis, ask GoDavaii's Health AI - it explains medical conditions in 90+ languages, free, with no signup. Tap "Ask GoDavaii AI about Sickle-cell thalassemia beta plus with crisis" above to get a personalised answer.

Source: ICD-10-CM 2025 (Centers for Medicare & Medicaid Services, public domain). Codes valid from October 1, 2024. CMS source ↗