Common side effects of Mirtazapine include Significant weight gain, Drowsiness, Increased appetite. Serious side effects include Agranulocytosis (rare) and Serotonin syndrome. Mirtazapine is classified as Atypical AD. Always consult a doctor if side effects persist.

Side Effects GuideAI-VerifiedAtypical AD

Mirtazapine Side Effects

Complete guide to Mirtazapine side effects — what's common, what's serious, which body systems are affected, and when to see a doctor.

Body impact map

Common
Serious
4
Common effects
3
Serious effects
4
Body systems

Common Side Effects

Usually mild · often resolve on their own

These side effects may occur in some patients taking Mirtazapine. Most are mild and improve as your body adjusts. Tell your doctor if any persist or worsen.

Significant weight gain
Whole body
Drowsiness
Head / Brain
Increased appetite
Stomach / GI
Dry mouth
Whole body

Serious Side Effects

Rare but urgent · seek immediate medical help

Stop taking Mirtazapine and seek immediate medical help if any of the following occur. Call 112 for emergencies.

Emergency · 112
Agranulocytosis (rare)
Whole body
Serotonin syndrome
Mental / Nervous
Suicidal thoughts
Mental / Nervous

Not a complete list. Report any unusual symptoms to your doctor immediately.

How to Minimize Side Effects

Simple steps that help

  • Take Mirtazapine exactly as prescribed by your doctor — never change the dose yourself.
  • Follow dosage timing instructions carefully (with food / empty stomach / at bedtime as directed).
  • Do not stop Mirtazapine suddenly without consulting your doctor — sudden discontinuation can be risky.
  • Report any new or unusual symptoms to your doctor promptly — early detection prevents complications.
  • Check drug interactions with GoDavaii AI before starting any new medicine, supplement, or even herbal remedy.
  • Avoid alcohol while on Mirtazapine unless your doctor has confirmed it is safe.
AI-Verified · Cross-checked against 40,000+ interaction database

Not medical advice

Individual responses to Mirtazapine vary — age, weight, existing conditions, and other medicines all matter. Always consult your doctor for personalized advice. For emergencies, call 112.

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