Simvastatin in pregnancy: classified as Category X. Simvastatin pregnancy safety: Category X — Contraindicated. Ezetimibe and simvastatin tablets Risk Summary Discontinue ezetimibe and simvastatin tablets when pr

Important Safety Warning

Simvastatin is classified as Contraindicated during pregnancy. Do not take this medicine without direct guidance from your obstetrician.

Pregnancy SafetyContraindicatedFDA Cat. XAI-Verified

Is Simvastatin safe during pregnancy?

Ezetimibe and simvastatin tablets Risk Summary Discontinue ezetimibe and simvastatin tablets when pregnancy is recognized. Alternatively, consider the ongoing therapeutic needs of the individual patient. Ezetimibe and simvastatin tablets decreases synthesis of cholesterol and possibly other biologically active substances derived from cholesterol; therefore, ezetimibe and simvastatin tablets may cause fetal harm when administered to pregnant patients based on the mechanism of action [see Clinical...

SAFECAUTIONAVOID

Overall verdict

Contraindicated

Trimester-by-Trimester Guide

40 weeks · 3 stages · different risks

AVOID
AVOID
AVOID
Week 1
Week 13
Week 27Week 40
Avoid

1st Trimester

Weeks 1–12 · Organs forming

Ezetimibe and simvastatin tablets Risk Summary Discontinue ezetimibe and simvastatin tablets when pregnancy is recognized. Alternatively, consider the ongoing therapeutic needs of the individual patient. Ezetimibe and simvastatin tablets decreases synthesis of cholesterol and possibly other biologically active substances derived from cholesterol; therefore, ezetimibe and simvastatin tablets may cause fetal harm when administered to pregnant patients based on the mechanism of action [see Clinical...

Avoid

2nd Trimester

Weeks 13–26 · Baby growing

Ezetimibe and simvastatin tablets Risk Summary Discontinue ezetimibe and simvastatin tablets when pregnancy is recognized. Alternatively, consider the ongoing therapeutic needs of the individual patient. Ezetimibe and simvastatin tablets decreases synthesis of cholesterol and possibly other biologically active substances derived from cholesterol; therefore, ezetimibe and simvastatin tablets may cause fetal harm when administered to pregnant patients based on the mechanism of action [see Clinical...

Avoid

3rd Trimester

Weeks 27–40 · Final development

Ezetimibe and simvastatin tablets Risk Summary Discontinue ezetimibe and simvastatin tablets when pregnancy is recognized. Alternatively, consider the ongoing therapeutic needs of the individual patient. Ezetimibe and simvastatin tablets decreases synthesis of cholesterol and possibly other biologically active substances derived from cholesterol; therefore, ezetimibe and simvastatin tablets may cause fetal harm when administered to pregnant patients based on the mechanism of action [see Clinical...

X

Category X — Never Use

Proven fetal abnormalities. Risk clearly outweighs any benefit.

Brands Available in India

Simvastatin is sold under these common brand names. All contain the same active ingredient, so safety during pregnancy is identical. Tap any brand for detailed info.

AI-Verified · Based on FDA classifications + peer-reviewed sources

Not medical advice

Every pregnancy is different. Always consult your obstetrician before taking any medicine. Drug safety classifications can change — verify current guidelines with your doctor. For emergencies, call 112.

Frequently Asked Questions

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