Piperacillin(4000mg)+ Tazobactum(500mg) in pregnancy: classified as Category C. Piperacillin(4000mg)+ Tazobactum(500mg) pregnancy safety: Category C - Use with caution. Risk Summary Piperacillin and tazobactam cross the placenta in humans. However, there are insufficie

Pregnancy SafetyUse With CautionFDA Cat. CAI-Verified

Is Piperacillin(4000mg)+ Tazobactum(500mg) safe during pregnancy?

Risk Summary Piperacillin and tazobactam cross the placenta in humans. However, there are insufficient data with piperacillin and/or tazobactam in pregnant women to inform a drug-associated risk for major birth defects and miscarriage. No fetal structural abnormalities were observed in rats or mice when piperacillin and tazobactam was administered intravenously during organogenesis at doses 1 to 2 times and 2 to 3 times the human dose of piperacillin and tazobactam, respectively, based on body-s...

SAFECAUTIONAVOID

Overall verdict

Use With Caution

Trimester-by-Trimester Guide

40 weeks · 3 stages · different risks

AVOID
AVOID
AVOID
Week 1
Week 13
Week 27Week 40
Avoid

1st Trimester

Weeks 1-12 · Organs forming

Risk Summary Piperacillin and tazobactam cross the placenta in humans. However, there are insufficient data with piperacillin and/or tazobactam in pregnant women to inform a drug-associated risk for major birth defects and miscarriage. No fetal structural abnormalities were observed in rats or mice when piperacillin and tazobactam was administered intravenously during organogenesis at doses 1 to 2 times and 2 to 3 times the human dose of piperacillin and tazobactam, respectively, based on body-s...

Avoid

2nd Trimester

Weeks 13-26 · Baby growing

Risk Summary Piperacillin and tazobactam cross the placenta in humans. However, there are insufficient data with piperacillin and/or tazobactam in pregnant women to inform a drug-associated risk for major birth defects and miscarriage. No fetal structural abnormalities were observed in rats or mice when piperacillin and tazobactam was administered intravenously during organogenesis at doses 1 to 2 times and 2 to 3 times the human dose of piperacillin and tazobactam, respectively, based on body-s...

Avoid

3rd Trimester

Weeks 27-40 · Final development

Risk Summary Piperacillin and tazobactam cross the placenta in humans. However, there are insufficient data with piperacillin and/or tazobactam in pregnant women to inform a drug-associated risk for major birth defects and miscarriage. No fetal structural abnormalities were observed in rats or mice when piperacillin and tazobactam was administered intravenously during organogenesis at doses 1 to 2 times and 2 to 3 times the human dose of piperacillin and tazobactam, respectively, based on body-s...

C

Category C - Use Cautiously

Animal studies show adverse effects; weigh benefits vs. risks.

Brands Available in India

Piperacillin(4000mg)+ Tazobactum(500mg) is sold in India under these common brand names. Check the strip or label: if a brand also contains other medicines, ask your doctor, because the extra ingredient changes the pregnancy advice. Tap any brand for detailed info.

AI-Verified · Based on FDA classifications + peer-reviewed sources

Not medical advice

Every pregnancy is different. Always consult your obstetrician before taking any medicine. Drug safety classifications can change, so verify current guidelines with your doctor. For emergencies, call 112.

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