Is Metronidazole safe during pregnancy?
Risk Summary While available studies cannot definitively establish the absence of risk, published data from case-control studies, cohort studies and meta-analyses have not established an association with metronidazole use during pregnancy and major birth defects, miscarriage or other adverse maternal or fetal outcomes (see Data). The background risk of major birth defects and miscarriage for the indicated population is unknown.
Overall verdict
Use With Caution
Trimester-by-Trimester Guide
40 weeks · 3 stages · different risks
1st Trimester
Weeks 1–12 · Organs forming
Risk Summary While available studies cannot definitively establish the absence of risk, published data from case-control studies, cohort studies and meta-analyses have not established an association with metronidazole use during pregnancy and major birth defects, miscarriage or other adverse maternal or fetal outcomes (see Data). The background risk of major birth defects and miscarriage for the indicated population is unknown.
2nd Trimester
Weeks 13–26 · Baby growing
Risk Summary While available studies cannot definitively establish the absence of risk, published data from case-control studies, cohort studies and meta-analyses have not established an association with metronidazole use during pregnancy and major birth defects, miscarriage or other adverse maternal or fetal outcomes (see Data). The background risk of major birth defects and miscarriage for the indicated population is unknown.
3rd Trimester
Weeks 27–40 · Final development
Risk Summary While available studies cannot definitively establish the absence of risk, published data from case-control studies, cohort studies and meta-analyses have not established an association with metronidazole use during pregnancy and major birth defects, miscarriage or other adverse maternal or fetal outcomes (see Data). The background risk of major birth defects and miscarriage for the indicated population is unknown.
Category B — Likely Safe
Animal studies show no risk, but limited human data available.
Not medical advice
Every pregnancy is different. Always consult your obstetrician before taking any medicine. Drug safety classifications can change — verify current guidelines with your doctor. For emergencies, call 112.
Frequently Asked Questions
Pregnancy specific sawaal? AI se directly pooch lo.
Metronidazole dose, safer alternatives, trimester-specific guidance — apni language mein.