Methylprednisolone in pregnancy: classified as Category C. Methylprednisolone pregnancy safety: Category C — Use with caution. Risk Summary Bupivacaine Hydrochloride Injection/Bupivacaine Hydrochloride and Epinephrine Injection

Pregnancy SafetyUse With CautionFDA Cat. CAI-Verified

Is Methylprednisolone safe during pregnancy?

Risk Summary Bupivacaine Hydrochloride Injection/Bupivacaine Hydrochloride and Epinephrine Injection is contraindicated for obstetrical paracervical block anesthesia. Its use in this technique has resulted in fetal bradycardia and death [see Contraindications , Warnings and Precautions ].

SAFECAUTIONAVOID

Overall verdict

Use With Caution

Trimester-by-Trimester Guide

40 weeks · 3 stages · different risks

AVOID
AVOID
AVOID
Week 1
Week 13
Week 27Week 40
Avoid

1st Trimester

Weeks 1–12 · Organs forming

Risk Summary Bupivacaine Hydrochloride Injection/Bupivacaine Hydrochloride and Epinephrine Injection is contraindicated for obstetrical paracervical block anesthesia. Its use in this technique has resulted in fetal bradycardia and death [see Contraindications , Warnings and Precautions ].

Avoid

2nd Trimester

Weeks 13–26 · Baby growing

Risk Summary Bupivacaine Hydrochloride Injection/Bupivacaine Hydrochloride and Epinephrine Injection is contraindicated for obstetrical paracervical block anesthesia. Its use in this technique has resulted in fetal bradycardia and death [see Contraindications , Warnings and Precautions ].

Avoid

3rd Trimester

Weeks 27–40 · Final development

Risk Summary Bupivacaine Hydrochloride Injection/Bupivacaine Hydrochloride and Epinephrine Injection is contraindicated for obstetrical paracervical block anesthesia. Its use in this technique has resulted in fetal bradycardia and death [see Contraindications , Warnings and Precautions ].

C

Category C — Use Cautiously

Animal studies show adverse effects; weigh benefits vs. risks.

Brands Available in India

Methylprednisolone is sold under these common brand names. All contain the same active ingredient, so safety during pregnancy is identical. Tap any brand for detailed info.

AI-Verified · Based on FDA classifications + peer-reviewed sources

Not medical advice

Every pregnancy is different. Always consult your obstetrician before taking any medicine. Drug safety classifications can change — verify current guidelines with your doctor. For emergencies, call 112.

Frequently Asked Questions

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