Is Gemcitabine(1000mg) safe during pregnancy?
Risk Summary Based on animal data and its mechanism of action, gemcitabine can cause fetal harm when administered to a pregnant woman [see Clinical Pharmacology ] . There are no available data on the use of gemcitabine in pregnant women. In animal reproduction studies, gemcitabine was teratogenic, embryotoxic, and fetotoxic in mice and rabbits (see Data ) . Advise pregnant women of the potential risk to a fetus [see Use in Specific Populations ] . In the U.S.
Overall verdict
Use With Caution
Trimester-by-Trimester Guide
40 weeks · 3 stages · different risks
1st Trimester
Weeks 1-12 · Organs forming
Risk Summary Based on animal data and its mechanism of action, gemcitabine can cause fetal harm when administered to a pregnant woman [see Clinical Pharmacology ] . There are no available data on the use of gemcitabine in pregnant women. In animal reproduction studies, gemcitabine was teratogenic, embryotoxic, and fetotoxic in mice and rabbits (see Data ) . Advise pregnant women of the potential risk to a fetus [see Use in Specific Populations ] . In the U.S.
2nd Trimester
Weeks 13-26 · Baby growing
Risk Summary Based on animal data and its mechanism of action, gemcitabine can cause fetal harm when administered to a pregnant woman [see Clinical Pharmacology ] . There are no available data on the use of gemcitabine in pregnant women. In animal reproduction studies, gemcitabine was teratogenic, embryotoxic, and fetotoxic in mice and rabbits (see Data ) . Advise pregnant women of the potential risk to a fetus [see Use in Specific Populations ] . In the U.S.
3rd Trimester
Weeks 27-40 · Final development
Risk Summary Based on animal data and its mechanism of action, gemcitabine can cause fetal harm when administered to a pregnant woman [see Clinical Pharmacology ] . There are no available data on the use of gemcitabine in pregnant women. In animal reproduction studies, gemcitabine was teratogenic, embryotoxic, and fetotoxic in mice and rabbits (see Data ) . Advise pregnant women of the potential risk to a fetus [see Use in Specific Populations ] . In the U.S.
Category C - Use Cautiously
Animal studies show adverse effects; weigh benefits vs. risks.
Brands Available in India
Gemcitabine(1000mg) is sold under these common brand names. All contain the same active ingredient, so safety during pregnancy is identical. Tap any brand for detailed info.
Not medical advice
Every pregnancy is different. Always consult your obstetrician before taking any medicine. Drug safety classifications can change — verify current guidelines with your doctor. For emergencies, call 112.
Frequently Asked Questions
Pregnancy specific sawaal? AI se directly pooch lo.
Gemcitabine(1000mg) dose, safer alternatives, trimester-specific guidance — apni language mein.