Is Doxorubicin(plain)(10mg) safe during pregnancy?
Risk Summary Based on findings in animals and its mechanism of action, doxorubicin hydrochloride liposome injection can cause fetal harm when administered to a pregnant woman; avoid the use of doxorubicin hydrochloride liposome injection during the 1 st trimester. In animal reproduction studies, doxorubicin hydrochloride liposome injection was embryotoxic in rats and abortifacient in rabbits following intravenous administration during organogenesis at doses approximately 0.
Overall verdict
Use With Caution
Trimester-by-Trimester Guide
40 weeks · 3 stages · different risks
1st Trimester
Weeks 1-12 · Organs forming
Risk Summary Based on findings in animals and its mechanism of action, doxorubicin hydrochloride liposome injection can cause fetal harm when administered to a pregnant woman; avoid the use of doxorubicin hydrochloride liposome injection during the 1 st trimester. In animal reproduction studies, doxorubicin hydrochloride liposome injection was embryotoxic in rats and abortifacient in rabbits following intravenous administration during organogenesis at doses approximately 0.
2nd Trimester
Weeks 13-26 · Baby growing
Risk Summary Based on findings in animals and its mechanism of action, doxorubicin hydrochloride liposome injection can cause fetal harm when administered to a pregnant woman; avoid the use of doxorubicin hydrochloride liposome injection during the 1 st trimester. In animal reproduction studies, doxorubicin hydrochloride liposome injection was embryotoxic in rats and abortifacient in rabbits following intravenous administration during organogenesis at doses approximately 0.
3rd Trimester
Weeks 27-40 · Final development
Risk Summary Based on findings in animals and its mechanism of action, doxorubicin hydrochloride liposome injection can cause fetal harm when administered to a pregnant woman; avoid the use of doxorubicin hydrochloride liposome injection during the 1 st trimester. In animal reproduction studies, doxorubicin hydrochloride liposome injection was embryotoxic in rats and abortifacient in rabbits following intravenous administration during organogenesis at doses approximately 0.
Category C - Use Cautiously
Animal studies show adverse effects; weigh benefits vs. risks.
Brands Available in India
Doxorubicin(plain)(10mg) is sold in India under these common brand names. Check the strip or label: if a brand also contains other medicines, ask your doctor, because the extra ingredient changes the pregnancy advice. Tap any brand for detailed info.
Not medical advice
Every pregnancy is different. Always consult your obstetrician before taking any medicine. Drug safety classifications can change, so verify current guidelines with your doctor. For emergencies, call 112.
Frequently Asked Questions
Pregnancy specific sawaal? AI se directly pooch lo.
Doxorubicin(plain)(10mg) dose, safer alternatives, trimester-specific guidance, apni language mein.