HL-60 Cells (also known as HL-60 Cell, HL 60 Cells): A promyelocytic cell line derived from a patient with ACUTE PROMYELOCYTIC LEUKEMIA. HL-60 cells lack specific markers for LYMPHOID CELLS but express surface receptors for FC FRAGMENTS and COMPLEMENT SYSTEM PROTEINS. They also exhibit phagocytic activity and responsiv

NIH MeSH · D018922Anatomy

HL-60 Cells

Also known asHL-60 Cell · HL 60 Cells · HL60 Cells · Cell, HL60 · Cells, HL60 · HL60 Cell

Definition

A promyelocytic cell line derived from a patient with ACUTE PROMYELOCYTIC LEUKEMIA. HL-60 cells lack specific markers for LYMPHOID CELLS but express surface receptors for FC FRAGMENTS and COMPLEMENT SYSTEM PROTEINS. They also exhibit phagocytic activity and responsiveness to chemotactic stimuli. (From Hay et al., American Type Culture Collection, 7th ed, pp127-8)

MeSH classification

  • A11.251.210.190.465
  • A11.251.860.180.465
  • A11.627.340.360.500

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Related concepts

Common questions about HL-60 Cells

What does HL-60 Cells mean in medicine?
A promyelocytic cell line derived from a patient with ACUTE PROMYELOCYTIC LEUKEMIA. HL-60 cells lack specific markers for LYMPHOID CELLS but express surface receptors for FC FRAGMENTS and COMPLEMENT SYSTEM PROTEINS. They also exhibit phagocytic activity and responsiveness to chemotactic stimuli. (From Hay et al., American Type Culture Collection, 7th ed, pp127-8) This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is HL-60 Cells known by any other names?
Yes. HL-60 Cells is also referred to as HL-60 Cell, HL 60 Cells, HL60 Cells, Cell, HL60 in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does HL-60 Cells sit in the medical classification?
HL-60 Cells falls under the broader medical category "Anatomy" in the MeSH hierarchy (tree numbers: A11.251.210.190.465, A11.251.860.180.465, A11.627.340.360.500). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of HL-60 Cells?
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Source: NIH MeSH 2026 (D018922) — National Library of Medicine, public domain. View official MeSH record ↗