A549 Cells (also known as A549 Cell, Cell, A549): An immortalized cell line derived from human ADENOCARCINOMA, ALVEOLAR basal epithelial cells isolated from the lungs of a male patient in 1972. The cell line is positive for KERATIN, can synthesize LECITHIN, and contains high levels of POLYUNSATURATED FATTY ACIDS in its

NIH MeSH · D000072283Anatomy

A549 Cells

Also known asA549 Cell · Cell, A549 · Cells, A549 · A549 Cell Line · A549 Cell Lines · Cell Line, A549 · Cell Lines, A549

Definition

An immortalized cell line derived from human ADENOCARCINOMA, ALVEOLAR basal epithelial cells isolated from the lungs of a male patient in 1972. The cell line is positive for KERATIN, can synthesize LECITHIN, and contains high levels of POLYUNSATURATED FATTY ACIDS in its PLASMA MEMBRANE. It is used as a model for PULMONARY ALVEOLI function and virus infections, as a TRANSFECTION host, and for PRECLINICAL DRUG EVALUATION.

MeSH classification

  • A11.251.210.190.080
  • A11.251.860.180.080
  • A11.436.054

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Common questions about A549 Cells

What does A549 Cells mean in medicine?
An immortalized cell line derived from human ADENOCARCINOMA, ALVEOLAR basal epithelial cells isolated from the lungs of a male patient in 1972. The cell line is positive for KERATIN, can synthesize LECITHIN, and contains high levels of POLYUNSATURATED FATTY ACIDS in its PLASMA MEMBRANE. It is used as a model for PULMONARY ALVEOLI function and virus infections, as a TRANSFECTION host, and for PRECLINICAL DRUG EVALUATION. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is A549 Cells known by any other names?
Yes. A549 Cells is also referred to as A549 Cell, Cell, A549, Cells, A549, A549 Cell Line in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does A549 Cells sit in the medical classification?
A549 Cells falls under the broader medical category "Anatomy" in the MeSH hierarchy (tree numbers: A11.251.210.190.080, A11.251.860.180.080, A11.436.054). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of A549 Cells?
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Source: NIH MeSH 2026 (D000072283) — National Library of Medicine, public domain. View official MeSH record ↗