Glucocorticoids
Also known asGlucocorticoid · Glucocorticoid Effect · Effect, Glucocorticoid · Glucorticoid Effects · Effects, Glucorticoid
Definition
A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.
MeSH classification
- D06.472.040.543
- D27.505.696.399.472.488
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11-Hydroxycorticosteroids
A group of corticosteroids bearing a hydroxy group at the 11-position.
17-alpha-Hydroxypregnenolone
A 21-carbon steroid that is converted from PREGNENOLONE by STEROID 17-ALPHA-HYDROXYLASE. It is an intermediate in the delta-5 pathway of bio…
17-Hydroxycorticosteroids
A group of hydroxycorticosteroids bearing a hydroxy group at the 17-position. Urinary excretion of these compounds is used as an index of ad…
17-Ketosteroids
Steroids that contain a ketone group at position 17.
18-Hydroxycorticosterone
11 beta,18,21-Trihydroxypregn-4-ene-3,20-dione.
18-Hydroxydesoxycorticosterone
An analog of desoxycorticosterone which is substituted by a hydroxyl group at the C-18 position.
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Source: NIH MeSH 2026 (D005938) — National Library of Medicine, public domain. View official MeSH record ↗