17-alpha-Hydroxypregnenolone (also known as 17 alpha Hydroxypregnenolone, Hydroxypregnenolone): A 21-carbon steroid that is converted from PREGNENOLONE by STEROID 17-ALPHA-HYDROXYLASE. It is an intermediate in the delta-5 pathway of biosynthesis of GONADAL STEROID HORMONES and the adrenal CORTICOSTEROIDS.

NIH MeSH · D006907Chemicals and Drugs

17-alpha-Hydroxypregnenolone

Also known as17 alpha Hydroxypregnenolone · Hydroxypregnenolone · 17 alpha-Hydroxypregnenolone · 17-Hydroxypregnenolone · 17 Hydroxypregnenolone · 17-Hydroxypregnenolone, (3beta,17alpha)-Isomer · 17alpha-Hydroxypregnenolone · 17alpha Hydroxypregnenolone · 17-Hydroxypregnenolone, (3alpha)-Isomer · 17-Hydroxypregnenolone, (3beta,13alpha,17alpha)-Isomer · 17-Hydroxypregnenolone, (3beta,13alpha)-Isomer

Definition

A 21-carbon steroid that is converted from PREGNENOLONE by STEROID 17-ALPHA-HYDROXYLASE. It is an intermediate in the delta-5 pathway of biosynthesis of GONADAL STEROID HORMONES and the adrenal CORTICOSTEROIDS.

MeSH classification

  • D04.210.500.745.745.725.395
  • D06.472.040.585.745.500
  • D06.472.334.851.687.500.500

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Common questions about 17-alpha-Hydroxypregnenolone

What does 17-alpha-Hydroxypregnenolone mean in medicine?
A 21-carbon steroid that is converted from PREGNENOLONE by STEROID 17-ALPHA-HYDROXYLASE. It is an intermediate in the delta-5 pathway of biosynthesis of GONADAL STEROID HORMONES and the adrenal CORTICOSTEROIDS. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is 17-alpha-Hydroxypregnenolone known by any other names?
Yes. 17-alpha-Hydroxypregnenolone is also referred to as 17 alpha Hydroxypregnenolone, Hydroxypregnenolone, 17 alpha-Hydroxypregnenolone, 17-Hydroxypregnenolone in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does 17-alpha-Hydroxypregnenolone sit in the medical classification?
17-alpha-Hydroxypregnenolone falls under the broader medical category "Chemicals and Drugs" in the MeSH hierarchy (tree numbers: D04.210.500.745.745.725.395, D06.472.040.585.745.500, D06.472.334.851.687.500.500). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of 17-alpha-Hydroxypregnenolone?
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Source: NIH MeSH 2026 (D006907) — National Library of Medicine, public domain. View official MeSH record ↗