Fanconi Syndrome (also known as Syndrome, Fanconi, Proximal Renal Tubular Dysfunction): A hereditary or acquired form of generalized dysfunction of the PROXIMAL KIDNEY TUBULE without primary involvement of the KIDNEY GLOMERULUS. It is usually characterized by the tubular wasting of nutrients and salts (GLUCOSE; AMINO A

NIH MeSH · D005198Diseases

Fanconi Syndrome

Also known asSyndrome, Fanconi · Proximal Renal Tubular Dysfunction · Fanconi Syndrome without Cystinosis · Fanconi Renotubular Syndrome · Renotubular Syndrome, Fanconi · Syndrome, Fanconi Renotubular · Renal Fanconi Syndrome · Fanconi Syndrome, Renal · Syndrome, Renal Fanconi · Luder-Sheldon Syndrome · Luder Sheldon Syndrome · Syndrome, Luder-Sheldon

Definition

A hereditary or acquired form of generalized dysfunction of the PROXIMAL KIDNEY TUBULE without primary involvement of the KIDNEY GLOMERULUS. It is usually characterized by the tubular wasting of nutrients and salts (GLUCOSE; AMINO ACIDS; PHOSPHATES; and BICARBONATES) resulting in HYPOKALEMIA; ACIDOSIS; HYPERCALCIURIA; and PROTEINURIA.

MeSH classification

  • C12.050.351.968.419.815.450
  • C12.200.777.419.815.450
  • C12.950.419.815.450
  • C16.320.831.450

Need clinical context, treatments, or patient-language explanation?

Ask GoDavaii AI about Fanconi Syndrome

Related concepts

Acidosis, Renal Tubular

A group of genetic disorders of the KIDNEY TUBULES characterized by the accumulation of metabolically produced acids with elevated plasma ch…

Common questions about Fanconi Syndrome

What does Fanconi Syndrome mean in medicine?
A hereditary or acquired form of generalized dysfunction of the PROXIMAL KIDNEY TUBULE without primary involvement of the KIDNEY GLOMERULUS. It is usually characterized by the tubular wasting of nutrients and salts (GLUCOSE; AMINO ACIDS; PHOSPHATES; and BICARBONATES) resulting in HYPOKALEMIA; ACIDOSIS; HYPERCALCIURIA; and PROTEINURIA. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is Fanconi Syndrome known by any other names?
Yes. Fanconi Syndrome is also referred to as Syndrome, Fanconi, Proximal Renal Tubular Dysfunction, Fanconi Syndrome without Cystinosis, Fanconi Renotubular Syndrome in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does Fanconi Syndrome sit in the medical classification?
Fanconi Syndrome falls under the broader medical category "Diseases" in the MeSH hierarchy (tree numbers: C12.050.351.968.419.815.450, C12.200.777.419.815.450, C12.950.419.815.450). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of Fanconi Syndrome?
For a plain-language explanation of Fanconi Syndrome - including symptoms, treatments and what it means for an Indian patient - ask GoDavaii's Health AI. It works in 22+ Indian languages, is free and needs no signup. Tap "Ask GoDavaii AI about Fanconi Syndrome" above.

Source: NIH MeSH 2026 (D005198) — National Library of Medicine, public domain. View official MeSH record ↗