Acidosis, Renal Tubular (also known as Renal Tubular Acidosis, Renal Tubular Acidosis, Type I): A group of genetic disorders of the KIDNEY TUBULES characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic ACIDOSIS. Defective renal acidification of URINE (p
NIH MeSH · D000141Diseases
Acidosis, Renal Tubular
Also known asRenal Tubular Acidosis · Renal Tubular Acidosis, Type I · Acidosis, Renal Tubular, Type I · Type I Renal Tubular Acidosis · Classic Distal Renal Tubular Acidosis · Renal Tubular Acidosis, Distal, Autosomal Dominant · Renal Tubular Acidosis I · Autosomal Dominant Distal Renal Tubular Acidosis · Renal Tubular Acidosis 1 · RTA, Classic Type · Classic Type RTA · Classic Type RTAs
Definition
A group of genetic disorders of the KIDNEY TUBULES characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic ACIDOSIS. Defective renal acidification of URINE (proximal tubules) or low renal acid excretion (distal tubules) can lead to complications such as HYPOKALEMIA, hypercalcinuria with NEPHROLITHIASIS and NEPHROCALCINOSIS, and RICKETS.
MeSH classification
C12.050.351.968.419.815.093
C12.200.777.419.815.093
C12.950.419.815.093
C16.320.831.093
C18.452.076.176.210
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What does Acidosis, Renal Tubular mean in medicine?
A group of genetic disorders of the KIDNEY TUBULES characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic ACIDOSIS. Defective renal acidification of URINE (proximal tubules) or low renal acid excretion (distal tubules) can lead to complications such as HYPOKALEMIA, hypercalcinuria with NEPHROLITHIASIS and NEPHROCALCINOSIS, and RICKETS. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is Acidosis, Renal Tubular known by any other names?
Yes. Acidosis, Renal Tubular is also referred to as Renal Tubular Acidosis, Renal Tubular Acidosis, Type I, Acidosis, Renal Tubular, Type I, Type I Renal Tubular Acidosis in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does Acidosis, Renal Tubular sit in the medical classification?
Acidosis, Renal Tubular falls under the broader medical category "Diseases" in the MeSH hierarchy (tree numbers: C12.050.351.968.419.815.093, C12.200.777.419.815.093, C12.950.419.815.093). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of Acidosis, Renal Tubular?
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