Calcium Signaling

Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.

Yes. Calcium Signaling is also referred to as Calcium Signalings, Signaling, Calcium, Signalings, Calcium, Calcium Puffs in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.

Calcium Signaling falls under the broader medical category "Phenomena and Processes" in the MeSH hierarchy (tree numbers: G02.111.820.800.100, G03.143.500.100, G04.835.800.100). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.

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