Biotransformation
Definition
The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II.
MeSH classification
- G03.171
- G03.787.225
- G07.690.725.225
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Absorption
The physical or physiological processes by which substances, tissue, cells, etc. take up or take in other substances or energy.
Absorption, Physiological
Uptake of substances by the body, tissues, or cells. The uptake may occur by various forms of BIOLOGICAL TRANSPORT or by simple DIFFUSION.
Acetylation
Formation of an acetyl derivative. (Stedman, 25th ed)
Acid-Base Equilibrium
The balance between acids and bases in the BODY FLUIDS. The pH (HYDROGEN-ION CONCENTRATION) of the arterial BLOOD provides an index for the …
Activation, Metabolic
The conversion of an exogenous substance by a biological system resulting in the production on an active metabolite.
Active Transport, Cell Nucleus
Gated transport mechanisms by which proteins or RNA are moved across the NUCLEAR MEMBRANE.
Acylation
The addition of an organic acid radical into a molecule.
ADP-Ribosylation
Post-translational modification of proteins with ADENOSINE DIPHOSPHATE RIBOSE.
Source: NIH MeSH 2026 (D001711) — National Library of Medicine, public domain. View official MeSH record ↗