Axon Guidance (also known as Neuronal Guidance, Neurite Guidance): The mechanism by which a neuronal process outgrows toward a target led by the GROWTH CONE. Local guidance cues are provided by cell surface proteins that act on the growing axon.

NIH MeSH · D000071437Phenomena and Processes

Axon Guidance

Also known asNeuronal Guidance · Neurite Guidance · Neural Guidance · Axonal Pathfinding · Neuronal Pathfinding · Neural Pathfinding · Axon Pathfinding · Pathfinding, Axon

Definition

The mechanism by which a neuronal process outgrows toward a target led by the GROWTH CONE. Local guidance cues are provided by cell surface proteins that act on the growing axon.

MeSH classification

  • G04.152.912.750.500
  • G07.345.500.325.377.687.750.750
  • G08.686.784.170.450.500.750.750
  • G11.561.620.750.500

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Related concepts

Axon Fasciculation

Process of organizing neighboring AXONS into a bundle or a fascicle during neurite outgrowth mediated by CELL ADHESION MOLECULES.

Common questions about Axon Guidance

What does Axon Guidance mean in medicine?
The mechanism by which a neuronal process outgrows toward a target led by the GROWTH CONE. Local guidance cues are provided by cell surface proteins that act on the growing axon. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is Axon Guidance known by any other names?
Yes. Axon Guidance is also referred to as Neuronal Guidance, Neurite Guidance, Neural Guidance, Axonal Pathfinding in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does Axon Guidance sit in the medical classification?
Axon Guidance falls under the broader medical category "Phenomena and Processes" in the MeSH hierarchy (tree numbers: G04.152.912.750.500, G07.345.500.325.377.687.750.750, G08.686.784.170.450.500.750.750). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of Axon Guidance?
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Source: NIH MeSH 2026 (D000071437) — National Library of Medicine, public domain. View official MeSH record ↗