Aicardi Syndrome (also known as Syndrome, Aicardi, Corpus Callosum, Agenesis Of, With Chorioretinal Abnormality): A rare genetic disorder characterized by partial or complete absence of the CORPUS CALLOSUM, resulting in infantile spasms, MENTAL RETARDATION, and lesions of the RETINA or OPTIC NERVE.
NIH MeSH · D058540Diseases
Aicardi Syndrome
Also known asSyndrome, Aicardi · Corpus Callosum, Agenesis Of, With Chorioretinal Abnormality · Aicardi's Syndrome · Syndrome, Aicardi's · Agenesis of Corpus Callosum with Infantile Spasms and Ocular Abnormalities · Callosal Agenesis and Ocular Abnormalities · Chorioretinal Anomalies with Acc · Agenesis of Corpus Callosum with Chorioretinal Abnormality
Definition
A rare genetic disorder characterized by partial or complete absence of the CORPUS CALLOSUM, resulting in infantile spasms, MENTAL RETARDATION, and lesions of the RETINA or OPTIC NERVE.
MeSH classification
C10.500.034.687
C11.270.019
C16.131.162
C16.131.666.034.687
C16.320.290.019
C16.320.322.030
Need clinical context, treatments, or patient-language explanation?
A rare genetic disorder characterized by partial or complete absence of the CORPUS CALLOSUM, resulting in infantile spasms, MENTAL RETARDATION, and lesions of the RETINA or OPTIC NERVE. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is Aicardi Syndrome known by any other names?
Yes. Aicardi Syndrome is also referred to as Syndrome, Aicardi, Corpus Callosum, Agenesis Of, With Chorioretinal Abnormality, Aicardi's Syndrome, Syndrome, Aicardi's in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does Aicardi Syndrome sit in the medical classification?
Aicardi Syndrome falls under the broader medical category "Diseases" in the MeSH hierarchy (tree numbers: C10.500.034.687, C11.270.019, C16.131.162). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of Aicardi Syndrome?
For a plain-language explanation of Aicardi Syndrome - including symptoms, treatments and what it means for an Indian patient - ask GoDavaii's Health AI. It works in 22+ Indian languages, is free and needs no signup. Tap "Ask GoDavaii AI about Aicardi Syndrome" above.