Adenomatous Polyposis Coli (also known as Adenomatous Polyposis Colus, Coli, Adenomatous Polyposis): A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of aff
A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.
MeSH classification
C04.557.470.035.215.100
C04.588.274.476.411.307.089
C04.700.100
C06.301.371.411.307.090
C06.405.249.411.307.090
C06.405.469.158.356.090
C06.405.469.491.307.090
C06.405.469.578.249
C16.320.700.100
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What does Adenomatous Polyposis Coli mean in medicine?
A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is Adenomatous Polyposis Coli known by any other names?
Yes. Adenomatous Polyposis Coli is also referred to as Adenomatous Polyposis Colus, Coli, Adenomatous Polyposis, Colus, Adenomatous Polyposis, Polyposis Coli, Adenomatous in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does Adenomatous Polyposis Coli sit in the medical classification?
Adenomatous Polyposis Coli falls under the broader medical category "Diseases" in the MeSH hierarchy (tree numbers: C04.557.470.035.215.100, C04.588.274.476.411.307.089, C04.700.100). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of Adenomatous Polyposis Coli?
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