1-Alkyl-2-acetylglycerophosphocholine Esterase (also known as 1 Alkyl 2 acetylglycerophosphocholine Esterase, Esterase, 1-Alkyl-2-acetylglycerophosphocholine): A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically
A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA.
MeSH classification
D08.811.277.352.100.680.750.937.249
Need clinical context, treatments, or patient-language explanation?
Common questions about 1-Alkyl-2-acetylglycerophosphocholine Esterase
What does 1-Alkyl-2-acetylglycerophosphocholine Esterase mean in medicine?
A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is 1-Alkyl-2-acetylglycerophosphocholine Esterase known by any other names?
Yes. 1-Alkyl-2-acetylglycerophosphocholine Esterase is also referred to as 1 Alkyl 2 acetylglycerophosphocholine Esterase, Esterase, 1-Alkyl-2-acetylglycerophosphocholine, PAF Acetylhydrolase II, Acetylhydrolase II, PAF in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does 1-Alkyl-2-acetylglycerophosphocholine Esterase sit in the medical classification?
1-Alkyl-2-acetylglycerophosphocholine Esterase falls under the broader medical category "Chemicals and Drugs" in the MeSH hierarchy (tree numbers: D08.811.277.352.100.680.750.937.249). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of 1-Alkyl-2-acetylglycerophosphocholine Esterase?
For a plain-language explanation of 1-Alkyl-2-acetylglycerophosphocholine Esterase - including symptoms, treatments and what it means for an Indian patient - ask GoDavaii's Health AI. It works in 22+ Indian languages, is free and needs no signup. Tap "Ask GoDavaii AI about 1-Alkyl-2-acetylglycerophosphocholine Esterase" above.