1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine (also known as H-7, H 7): A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.

NIH MeSH · D019307Chemicals and Drugs

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine

Also known asH-7 · H 7 · 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine

Definition

A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.

MeSH classification

  • D02.886.590.700.545
  • D03.383.606.527
  • D03.633.100.531.400

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Related concepts

Common questions about 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine

What does 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine mean in medicine?
A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine known by any other names?
Yes. 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine is also referred to as H-7, H 7, 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine sit in the medical classification?
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine falls under the broader medical category "Chemicals and Drugs" in the MeSH hierarchy (tree numbers: D02.886.590.700.545, D03.383.606.527, D03.633.100.531.400). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine?
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Source: NIH MeSH 2026 (D019307) — National Library of Medicine, public domain. View official MeSH record ↗