Can I take Cyclosporine with Sofosbuvir?
Cyclosporine and Sofosbuvir can generally be taken together with standard precautions. FDA label for Sofosbuvir references interaction with Cyclosporine. The use of OATP inhibitors which may substantially increase exposure of voxilaprevir (e.g., cyclosporine) with VOSEVI is not recommended [see Clinical Pharmacology ].
Brand names: Cyclosporine - Neoral, Sandimmune (US)
Quick verdict
Yes - Cyclosporine and Sofosbuvir can usually be combined.
Cyclosporine and Sofosbuvir can generally be taken together with standard precautions. FDA label for Sofosbuvir references interaction with Cyclosporine. The use of OATP inhibitors which may substantially increase exposure of voxilaprevir (e.g., cyclosporine) with VOSEVI is not recommended [see Clinical Pharmacology ].
Is it safe to take Cyclosporine with Sofosbuvir? Explain the interaction, what to watch for, and safer timing.
How They Interact
The science in one sentence
FDA label for Sofosbuvir references interaction with Cyclosporine. The use of OATP inhibitors which may substantially increase exposure of voxilaprevir (e.g., cyclosporine) with VOSEVI is not recommended [see Clinical Pharmacology ].
Why this matters
FDA label for Sofosbuvir references interaction with Cyclosporine. The use of OATP inhibitors which may substantially increase exposure of voxilaprevir (e.g., cyclosporine) with VOSEVI is not recommended [see Clinical Pharmacology ].
How to Use Smartly
Simple rules that protect you
- Always tell your doctor/pharmacist about ALL medicines you take - prescriptions, OTC, supplements, and herbal products.
- Keep a current medicine list with doses and timings - photo on your phone is enough.
- Read medicine labels for timing (with food / empty stomach) before combining.
- Even 'safe' combinations need monitoring - note any unusual symptoms in the first few days.
- Use GoDavaii AI to double-check before adding any new medicine, supplement, or desi ilaaj.
Not medical advice
Individual responses vary based on dose, timing, health conditions, and other medicines. Always consult your doctor or pharmacist before combining medicines. For emergencies, call 112.
Source
FDA drug label for Sofosbuvir (via openFDA). View source ↗
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