Codeine and Gabapentin: High risk - avoid combining interaction. Avoid combining these medicines. High risk. Avoid taking Codeine with Gabapentin unless your pharmacist or doctor approves.

Drug InteractionHigh Risk - AvoidAI-VerifiedCategory · general

Can I take Codeine with Gabapentin?

Codeine and Gabapentin should not be combined without explicit medical guidance.

Brand names: Gabapentin - Neurontin (US)

CodeineMEDICINE AGabapentinMEDICINE B
Avoid combining
Do not combine

Quick verdict

No - avoid combining Codeine with Gabapentin.

High Risk - Avoid. Do not combine.

Ask GoDavaii AI about this combination

Is it safe to take Codeine with Gabapentin? Explain the interaction, what to watch for, and safer timing.

Interaction text from an FDA label for a product containing Gabapentin (not specific to Codeine)

General label text, not a pair-specific study

Concentrations increased by morphine; may need dose adjustment ( 5.4 , 7.1 ) 7.1 Opioids Respiratory depression and sedation, sometimes resulting in death, have been reported following co-administration of gabapentin with opioids (e.g., morphine, hydrocodone, oxycodone, buprenorphine) [see Warnings and Precautions ] .

This is general interaction text from the label of a product that contains Gabapentin. It does not mention Codeine, so it does not show how Codeine and Gabapentin affect each other. The verdict above comes from the GoDavaii interaction dataset. Ask your pharmacist to check both medicines' labels before you combine them.

Questions to ask your pharmacist

  • Does Codeine change how Gabapentin works, or the other way round?
  • Should I take Codeine and Gabapentin at different times of day?
  • Which side effects should I watch for while taking both?
  • Is there a better option if this combination does not suit me?

Why to Avoid

Simple rules that protect you

  • Always tell your doctor/pharmacist about ALL medicines you take - prescriptions, OTC, supplements, and herbal products.
  • Keep a current medicine list with doses and timings - photo on your phone is enough.
  • Read medicine labels for timing (with food / empty stomach) before combining.
  • Do NOT combine Codeine with Gabapentin without explicit doctor approval.
  • Use GoDavaii AI to double-check before adding any new medicine, supplement, or desi ilaaj.

If you've already taken both medicines and feel unwell (unusual bleeding, severe stomach pain, confusion, breathing issues), get medical help now.

Emergency · 112
AI-Verified · Cross-checked against 93,000+ interaction database

Not medical advice

Individual responses vary based on dose, timing, health conditions, and other medicines. Always consult your doctor or pharmacist before combining medicines. For emergencies, call 112.

Source

FDA drug label for Gabapentin (via openFDA). View source ↗

General label text for Gabapentin; not a pair-specific study.

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