Cimetidine and Melatonin: Low risk interaction. Can be taken together with caution. Low risk. Cimetidine and Melatonin can usually be taken together with standard precautions.

Drug InteractionSafe - Low RiskAI-VerifiedCategory · general

Can I take Cimetidine with Melatonin?

Cimetidine and Melatonin can generally be taken together with standard precautions.

Brand names: Cimetidine - Tagamet (US)

CimetidineMEDICINE AMelatoninMEDICINE B
Can be combined
With standard precautions

Quick verdict

Yes - Cimetidine and Melatonin can usually be combined.

Safe - Low Risk. With standard precautions.

Ask GoDavaii AI about this combination

Is it safe to take Cimetidine with Melatonin? Explain the interaction, what to watch for, and safer timing.

Interaction text from an FDA label for a product containing Cimetidine (not specific to Melatonin)

General label text, not a pair-specific study

Drug Interactions Cimetidine tablets, apparently through an effect on certain microsomal enzyme systems, has been reported to reduce the hepatic metabolism of warfarin-type anticoagulants, phenytoin, propranolol, nifedipine, chlordiazepoxide, diazepam, certain tricyclic antidepressants, lidocaine, theophylline, and metronidazole, thereby delaying elimination and increasing blood levels of these dr...

This is general interaction text from the label of a product that contains Cimetidine. It does not mention Melatonin, so it does not show how Cimetidine and Melatonin affect each other. The verdict above comes from the GoDavaii interaction dataset. Ask your pharmacist to check both medicines' labels before you combine them.

Questions to ask your pharmacist

  • Does Cimetidine change how Melatonin works, or the other way round?
  • Should I take Cimetidine and Melatonin at different times of day?
  • Which side effects should I watch for while taking both?
  • Is there a better option if this combination does not suit me?

How to Use Smartly

Simple rules that protect you

  • Always tell your doctor/pharmacist about ALL medicines you take - prescriptions, OTC, supplements, and herbal products.
  • Keep a current medicine list with doses and timings - photo on your phone is enough.
  • Read medicine labels for timing (with food / empty stomach) before combining.
  • Even 'safe' combinations need monitoring - note any unusual symptoms in the first few days.
  • Use GoDavaii AI to double-check before adding any new medicine, supplement, or desi ilaaj.
AI-Verified · Cross-checked against 93,000+ interaction database

Not medical advice

Individual responses vary based on dose, timing, health conditions, and other medicines. Always consult your doctor or pharmacist before combining medicines. For emergencies, call 112.

Source

FDA drug label for Cimetidine (via openFDA). View source ↗

General label text for Cimetidine; not a pair-specific study.

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