Can I take Apixaban with Mefenamic Acid?
Apixaban and Mefenamic Acid should not be combined without explicit medical guidance.
Brand names: Apixaban - Eliquis (US)
Quick verdict
No - avoid combining Apixaban with Mefenamic Acid.
High Risk - Avoid. Do not combine.
Is it safe to take Apixaban with Mefenamic Acid? Explain the interaction, what to watch for, and safer timing.
Interaction text from an FDA label for a product containing Mefenamic Acid (not specific to Apixaban)
General label text, not a pair-specific study
Drug Interactions See Table 2 for clinically significant drug interactions with mefenamic acid. $ Table 2: Clinically Significant Drug Interactions with Mefenamic Acid Drugs That Interfere with Hemostasis Clinical Impact: Mefenamic acid and anticoagulants such as warfarin have a synergistic effect on bleeding.
This is general interaction text from the label of a product that contains Mefenamic Acid. It does not mention Apixaban, so it does not show how Apixaban and Mefenamic Acid affect each other. The verdict above comes from the GoDavaii interaction dataset. Ask your pharmacist to check both medicines' labels before you combine them.
Questions to ask your pharmacist
- Does Apixaban change how Mefenamic Acid works, or the other way round?
- Should I take Apixaban and Mefenamic Acid at different times of day?
- Which side effects should I watch for while taking both?
- Is there a better option if this combination does not suit me?
Why to Avoid
Simple rules that protect you
- Always tell your doctor/pharmacist about ALL medicines you take - prescriptions, OTC, supplements, and herbal products.
- Keep a current medicine list with doses and timings - photo on your phone is enough.
- Read medicine labels for timing (with food / empty stomach) before combining.
- Do NOT combine Apixaban with Mefenamic Acid without explicit doctor approval.
- Use GoDavaii AI to double-check before adding any new medicine, supplement, or desi ilaaj.
If you've already taken both medicines and feel unwell (unusual bleeding, severe stomach pain, confusion, breathing issues), get medical help now.
Emergency · 112Not medical advice
Individual responses vary based on dose, timing, health conditions, and other medicines. Always consult your doctor or pharmacist before combining medicines. For emergencies, call 112.
Source
FDA drug label for Mefenamic Acid (via openFDA). View source ↗
General label text for Mefenamic Acid; not a pair-specific study.
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