Can I take Acalabrutinib with Indomethacin?
Acalabrutinib and Indomethacin should not be combined without explicit medical guidance.
Brand names: Indomethacin - Indocin (US)
Quick verdict
No - avoid combining Acalabrutinib with Indomethacin.
High Risk - Avoid. Do not combine.
Is it safe to take Acalabrutinib with Indomethacin? Explain the interaction, what to watch for, and safer timing.
Interaction text from an FDA label for a product containing Indomethacin (not specific to Acalabrutinib)
General label text, not a pair-specific study
See Table 2 for clinically significant drug interactions with indomethacin. Table 2 Clinically Significant Drug Interactions with Indomethacin Drugs That Interfere with Hemostasis Clinical Impact: Indomethacin and anticoagulants such as warfarin have a synergistic effect on bleeding.
This is general interaction text from the label of a product that contains Indomethacin. It does not mention Acalabrutinib, so it does not show how Acalabrutinib and Indomethacin affect each other. The verdict above comes from the GoDavaii interaction dataset. Ask your pharmacist to check both medicines' labels before you combine them.
Questions to ask your pharmacist
- Does Acalabrutinib change how Indomethacin works, or the other way round?
- Should I take Acalabrutinib and Indomethacin at different times of day?
- Which side effects should I watch for while taking both?
- Is there a better option if this combination does not suit me?
Why to Avoid
Simple rules that protect you
- Always tell your doctor/pharmacist about ALL medicines you take - prescriptions, OTC, supplements, and herbal products.
- Keep a current medicine list with doses and timings - photo on your phone is enough.
- Read medicine labels for timing (with food / empty stomach) before combining.
- Do NOT combine Acalabrutinib with Indomethacin without explicit doctor approval.
- Use GoDavaii AI to double-check before adding any new medicine, supplement, or desi ilaaj.
If you've already taken both medicines and feel unwell (unusual bleeding, severe stomach pain, confusion, breathing issues), get medical help now.
Emergency · 112Not medical advice
Individual responses vary based on dose, timing, health conditions, and other medicines. Always consult your doctor or pharmacist before combining medicines. For emergencies, call 112.
Source
FDA drug label for Indomethacin (via openFDA). View source ↗
General label text for Indomethacin; not a pair-specific study.
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