Can I take Abemaciclib with Fluconazole?

Drug Interaction Studies (See PRECAUTIONS, Drug Interactions) Oral contraceptives: Oral contraceptives were administered as a single dose both before and after the oral administration of fluconazole 50 mg once daily for 10 days in 10 healthy women. There was no significant difference in ethinyl estradiol or levonorgestrel AUC after the administration of 50 mg of fluconazole.

This is general interaction text from the label of a product that contains Fluconazole. It does not mention Abemaciclib, so it does not show how Abemaciclib and Fluconazole affect each other. The verdict above comes from the GoDavaii interaction dataset. Ask your pharmacist to check both medicines' labels before you combine them.

Questions to ask your pharmacist

• Does Abemaciclib change how Fluconazole works, or the other way round?
• Should I take Abemaciclib and Fluconazole at different times of day?
• Which side effects should I watch for while taking both?
• Is there a better option if this combination does not suit me?

• Always tell your doctor/pharmacist about ALL medicines you take - prescriptions, OTC, supplements, and herbal products.
• Keep a current medicine list with doses and timings - photo on your phone is enough.
• Read medicine labels for timing (with food / empty stomach) before combining.
• Even 'safe' combinations need monitoring - note any unusual symptoms in the first few days.
• Use GoDavaii AI to double-check before adding any new medicine, supplement, or desi ilaaj.